Congenic mapping of the insulin-dependent diabetes (Idd) gene, Idd10, localizes two genes mediating the Idd10 effect and eliminates the candidate Fcgr1.

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Article

Congenic mapping of the insulin-dependent diabetes (Idd) gene, Idd10, localizes two genes mediating the Idd10 effect and eliminates the candidate Fcgr1.

Journal of immunology (Baltimore, Md. : 1950) - 15 Aug 1997

Podolin P L, Denny P, Lord C J, Hill N J, Todd J A, Peterson L B, Wicker L S, Lyons P A

Abstract excerpt

The development of autoimmune diabetes in the nonobese diabetic (NOD) mouse is under the control of multiple insulin-dependent diabetes (Idd) genes. The Idd3 gene, originally defined as a broad peak of linkage on mouse chromosome 3, was subsequently identified as two genes, Idd3 and Idd10, separa...

Topics

Alleles
Animals
Chromosome Mapping
Diabetes Mellitus, Type 1
Female
Mice
Mice, Inbred C57BL
Mice, Inbred NOD
Receptors, IgG

Source

Open in PubMed

Identifiers

PMID: 9257847

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9257847-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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