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Article

Effect of secondary structure on single nucleotide polymorphism detection with a porous microarray matrix; implications for probe selection.

BioTechniques - 1 May 2003

Anthony R M, Schuitema A R J, Chan A B, Boender P J, Klatser P R, Oskam L

Abstract excerpt

Oligonucleotide arrays capable of detecting single nucleotide polymorphisms (SNPs) from amplified nucleic acid have many applications. The expected SNP is usually placed approximately in the center of the probe to ensure the maximum shift in Tm between complementary and SNP sequences. Unfortunate...

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PMID: 12765035
DOI: 10.2144/03345dd05

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-12765035-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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