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Article

Molecular-beacon-based tricomponent probe for SNP analysis in folded nucleic acids.

Chemistry (Weinheim an der Bergstrasse, Germany) - 11 Nov 2011

Nguyen Camha, Grimes Jeffrey, Gerasimova Yulia V, Kolpashchikov Dmitry M

Abstract excerpt

Hybridization probes are often inefficient in the analysis of single-stranded DNA or RNA that are folded in stable secondary structures. A molecular beacon (MB) probe is a short DNA hairpin with a fluorophore and a quencher attached to opposite sides of the oligonucleotide. The probe is widely used in real-time analysis of specific DNA and RNA sequences. This study demonstrates how a conventional MB probe can be...

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PMID: 21956816
DOI: 10.1002/chem.201101987
PMCID: PMC3221966

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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