Article
Three-dimensional microarray platform applied to single nucleotide polymorphism analysis.
Biotechnology and bioengineering - 5 Jul 2004
Stimpson Donald I, Knepper Sheila M, Shida Miho, Obata Kimimichi, Tajima Hideji
Abstract excerpt
Bio-Strand, Inc., has developed a novel DNA microarray platform utilizing a three-dimensional (3D) DNA format. DNA probes or polymerase chain reaction (PCR) products are spotted onto a thread-like scaffold, which is then wound onto a cylindrical core. By wrapping the thread around the core, high efficiencies are achieved in sample analysis. Using allele-specific oligo (ASO) competitive hybridization (with Cy5...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
