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Article

Designed structural-rearrangement of an active group I ribozyme.

Journal of biochemistry - 1 Feb 2003

Ikawa Yoshiya, Inoue Tan

Abstract excerpt

The catalytic core of the Tetrahyemena group I ribozyme consists of two functionally different domains, P4-P6 and P3-P7, that are conjugated via multiple tertiary interactions. The sequence encoding the P3-P7 domain is divided into two fragments in its primary sequence although the two domains are physically separable in the three dimensional (3D-) structure of the ribozyme: The sequence encoding the P4-P6 domain...

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Identifiers

PMID: 12761181
DOI: 10.1093/jb/mvg023

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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