Article
Installation of orthogonality to the interface that assembles two modular domains in the Tetrahymena group I ribozyme.
Journal of bioscience and bioengineering - 1 Apr 2014
Tanaka Takahiro, Furuta Hiroyuki, Ikawa Yoshiya
Abstract excerpt
Two modular elements (P5abc and ΔP5) in the Tetrahymena group I ribozyme can be separated physically to generate a two-piece ribozyme derivative consisting of a separately prepared P5abc (P5 RNA) and the rest of the intron (ΔP5 RNA). Molecular recognition in the interface assembling P5 RNA and ΔP...
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