Article
deep-orange and carnation define distinct stages in late endosomal biogenesis in Drosophila melanogaster.
The Journal of cell biology - 12 May 2003
Sriram V, Krishnan K S, Mayor Satyajit
Abstract excerpt
Endosomal degradation is severely impaired in primary hemocytes from larvae of eye color mutants of Drosophila. Using high resolution imaging and immunofluorescence microscopy in these cells, products of eye color genes, deep-orange (dor) and carnation (car), are localized to large multivesicular Rab7-positive late endosomes containing Golgi-derived enzymes. These structures mature into small sized Dor-negative,...
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