Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A dual function for Deep orange in programmed autophagy in the Drosophila melanogaster fat body.

Experimental cell research - 1 Jul 2006

Lindmo Karine, Simonsen Anne, Brech Andreas, Finley Kim, Rusten Tor Erik, Stenmark Harald

Abstract excerpt

Lysosomal degradation of cytoplasm by way of autophagy is essential for cellular amino acid homeostasis and for tissue remodeling. In insects such as Drosophila, autophagy is developmentally upregulated in the larval fat body prior to metamorphosis. Here, autophagy is induced by the hormone ecdysone through down-regulation of the autophagy-suppressive phosphoinositide 3-kinase (PI3K) signaling pathway. In yeast,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Autophagy
Share to Down-Regulation
Share to Drosophila Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Ecdysone

Share to Fat Body

Share to Phosphatidylinositol 3-Kinases

Share to PTEN Phosphohydrolase

Source

Identifiers

PMID: 16600212
DOI: 10.1016/j.yexcr.2006.03.002

Genes

PTEN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A dual function for Deep orange in programmed autophagy in the Drosophila melanogaster fat body.PMID 16600212Read ↗

Programmed Autophagy in the Drosophila Fat Body Is Induced by Ecdysone through Regulation of the PI3K PathwaySemantic proximity Read ↗

A genetic screen in Drosophila reveals novel cytoprotective functions of the autophagy-lysosome pathway.Semantic proximity Read ↗

Autophagic programmed cell death in DrosophilaSemantic proximity Read ↗

Analysis of Drosophila Atg8 proteins reveals multiple lipidation-independent rolesSemantic proximity Read ↗

Dynamin Regulates Autophagy by Modulating Lysosomal Function.Semantic proximity Read ↗

Eating on the fly: Function and regulation of autophagy during cell growth, survival and death in DrosophilaSemantic proximity Read ↗

Autophagy and cell death in the fly.Semantic proximity Read ↗

Autophagy functions in programmed cell deathSemantic proximity Read ↗

Autophagic degradation of dBruce controls DNA fragmentation in nurse cells during late <i>Drosophila melanogaster</i> oogenesisSemantic proximity Read ↗

A genomic screen identifies AUT8 as a novel gene essential for autophagy in the yeast Saccharomyces cerevisiae.Semantic proximity Read ↗

Interaction of the HOPS complex with Syntaxin 17 mediates autophagosome clearance in Drosophila.Semantic proximity Read ↗

Drosophila as a model to understand autophagy deregulation in human disorders.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.