Article

Changes in endolysosomal organization define a pre-degenerative state in the <i>crumbs</i> mutant <i>Drosophila</i> retina

2019-07-12

Abstract excerpt

Mutations in the epithelial polarity gene crumbs ( crb ) lead to retinal degeneration in Drosophila and in humans. The overall morphology of the retina and its deterioration in Drosophila crb mutants has been well-characterized, but the cell biological origin of the degeneration is not well understood. Degenerative conditions in the retina and elsewhere in the nervous system often involve defects in degradativ...

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Literature Corpus work: 08a206e1-f58c-5ae7-8211-57603d95a360
DOI: 10.1101/701144

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