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Article

Rab6 Is Required for Multiple Apical Transport Pathways but Not the Basolateral Transport Pathway in Drosophila Photoreceptors.

PLoS genetics - 1 Feb 2016

Iwanami Nozomi, Nakamura Yuri, Satoh Takunori, Liu Ziguang, Satoh Akiko K

Abstract excerpt

Polarized membrane trafficking is essential for the construction and maintenance of multiple plasma membrane domains of cells. Highly polarized Drosophila photoreceptors are an excellent model for studying polarized transport. A single cross-section of Drosophila retina contains many photoreceptors with 3 clearly differentiated plasma membrane domains: a rhabdomere, stalk, and basolateral membrane. Genome-wide...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 26890939
DOI: 10.1371/journal.pgen.1005828
PMCID: PMC4758697

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Rab6 Is Required for Multiple Apical Transport Pathways but Not the Basolateral Transport Pathway in Drosophila Photoreceptors.PMID 26890939Read ↗

Identification of genes required for apical protein trafficking in Drosophila photoreceptor cellsSemantic proximity Read ↗

Rab6 regulation of rhodopsin transport in Drosophila.Semantic proximity Read ↗

GPI biosynthesis is essential for rhodopsin sorting at the trans-Golgi network in Drosophila photoreceptors.Semantic proximity Read ↗

The V-ATPase V1 subunit A1 is required for rhodopsin anterograde trafficking in Drosophila.Semantic proximity Read ↗

A role for rhodopsin in a signal transduction cascade that regulates membrane trafficking and photoreceptor polarity.Semantic proximity Read ↗

REEP6 mediates trafficking of a subset of Clathrin-coated vesicles and is critical for rod photoreceptor function and survival.Semantic proximity Read ↗

The Gos28 SNARE protein mediates intra-Golgi transport of rhodopsin and is required for photoreceptor survival.Semantic proximity Read ↗

The retromer complex is required for rhodopsin recycling and its loss leads to photoreceptor degeneration.Semantic proximity Read ↗

Drosophila fabp is required for light-dependent Rhodopsin-1 clearance and photoreceptor survival.Semantic proximity Read ↗

Differential activation of rhodopsin triggers distinct endocytic trafficking and recycling in vivo via differential phosphorylation.Semantic proximity Read ↗

Mutation in Rab11 results in abnormal organization of ommatidial cells and activation of JNK signaling in the Drosophila eye.Semantic proximity Read ↗

Rhabdomere biogenesis in Drosophila photoreceptors is acutely sensitive to phosphatidic acid levels.Semantic proximity Read ↗

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