Article
A role for the deep orange and carnation eye color genes in lysosomal delivery in Drosophila.
Molecular cell - 1 Oct 1999
Sevrioukov E A, He J P, Moghrabi N, Sunio A, Krämer H
Abstract excerpt
Deep orange and carnation are two of the classic eye color genes in Drosophila. Here, we demonstrate that Deep orange is part of a protein complex that localizes to endosomal compartments. A second component of this complex is Carnation, a homolog of Sec1p-like regulators of membrane fusion. Because complete loss of deep orange function is lethal, the role of this complex in intracellular trafficking was analyzed...
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