Shibire mutations reveal distinct dynamin-independent and -dependent endocytic pathways in primary cultures of Drosophila hemocytes.

doi:10.1242/jcs.00637

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Article

Shibire mutations reveal distinct dynamin-independent and -dependent endocytic pathways in primary cultures of Drosophila hemocytes.

Journal of cell science - 15 Aug 2003

Guha A, Sriram V, Krishnan K S, Mayor S

Abstract excerpt

We have developed a primary cell culture system derived from embryonic and larval stages of Drosophila. This allows for high-resolution imaging and genetic analyses of endocytic processes. Here, we have investigated endocytic pathways of three types of molecules: an endogenous receptor that binds anionic ligands (ALs), glycosylphosphatidylinositol (GPI)-anchored protein (GPI-AP), and markers of the fluid phase in...

Topics

Animals
Cells, Cultured
Clathrin-Coated Vesicles
Drosophila
Drosophila Proteins
Dynamins
Embryo, Nonmammalian
Endocytosis
Endosomes
Glycosylphosphatidylinositols
Hemocytes

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Larva

Microscopy, Fluorescence

Models, Molecular

Mutation

Pinocytosis

Receptors, Cell Surface

rab5 GTP-Binding Proteins

Source

Open in PubMed

Identifiers

PMID: 12857788
DOI: 10.1242/jcs.00637

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