Article
Drosophila GGA model: an ultimate gateway to GGA analysis.
Traffic (Copenhagen, Denmark) - 1 Dec 2011
Eissenberg Joel C, Ilvarsonn Anne M, Sly William S, Waheed Abdul, Krzyzanek Vladislav, Pohlmann Regina, Waschkau Daniela, Kretzschmar Doris, Dennes André C
Abstract excerpt
Golgi-localized, γ-ear-containing, ADP ribosylation factor-binding (GGA) proteins are monomeric adaptors implicated in clathrin-mediated vesicular transport between the trans Golgi network and endosomes, characterized mainly from cell culture analysis of lysosomal sorting. To provide the first demonstration of GGA's role in vivo, we used Drosophila which has a single GGA and a single lysosomal sorting receptor,...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
