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Article

Modulation of HLA class I expression in multidrug-resistant human rhabdomyosarcoma cells.

Neoplasma - 1 Jan 2003

Melguizo C, Prados J, Marchal J A, Vélez C, Carrillo E, Boulaiz H, Sánchez-Montesinos I, Madeddu R, Aránega A

Abstract excerpt

An abnormal HLA expression has been detected in some tumors including rhabdomyosarcoma (RMS). Classical cytotoxic treatment of these tumors, the most common childhood soft tissue malignancy, may induce multidrug resistance (MDR) associated with the expression of a 170-kDa membrane-associated glycoprotein (P-glycoprotein). In order to analyse the connection between modulation of HLA expression and the development...

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PMID: 12740641

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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