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Article

Characterization and modulation of drug resistance of human paediatric rhabdomyosarcoma cell lines.

British journal of cancer - 1 Aug 2000

Cocker H A, Pinkerton C R, Kelland L R

Abstract excerpt

The role of multidrug resistance (MDR) and p53 functional status in the treatment of paediatric rhabdomyosarcoma is unclear. We have characterized a panel of seven human rhabdomyosarcoma cell lines for MDR and p53 phenotype. None of the cell lines had P-glycoprotein (P-gp) or multidrug resistance-related protein (MRP) detectable by Western blotting, whereas immunohistochemistry suggested that very low levels of...

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Identifiers

PMID: 10917549
DOI: 10.1054/bjoc.2000.1273
PMCID: PMC2374566

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Source receipt: pubmed, retrieved 7 Sept 2026.

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