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Article

Multidrug resistance proteins in rhabdomyosarcomas

1 Apr 2003

Abstract excerpt

BACKGROUND: Pediatric rhabdomyosarcomas (RMS) have a more advantageous prognosis after multimodality treatment compared with adult RMS, which might be related to a decreased sensitivity to chemotherapy in adults. Resistance to chemotherapy might be conveyed by the multidrug resistance (MDR)-associated proteins P-glycoprotein (P-gp), multidrug resistance-associated protein 1 (MRP1), and lung resistance-related...

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PMID: 12673730
DOI: 10.1002/cncr.11259

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