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Article

Influence of chemosensitizers on resistance mechanisms in daunorubicin-resistant Ehrlich ascites tumour cells.

Cancer chemotherapy and pharmacology - 1 Jun 2002

Nielsen Dorte, Eriksen Jens, Maare Christian, Friche Ellen, Skovsgaard Torben

Abstract excerpt

AIM: To determine whether treatment with chemosensitizers influences the development of the drug-resistant phenotype. METHODS: Three sublines were developed from the sensitive Ehrlich ascites tumour cell line (EHR2) and six sublines from the EHR2/DNR cell line positive for P-glycoprotein (PGP) by treatment with daunorubicin (DNR), a combination of DNR and verapamil (VER), or a combination of DNR and cyclosporin A...

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Identifiers

PMID: 12107549
DOI: 10.1007/s00280-002-0436-4

Genes

PGP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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