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Article

The multidrug resistance phenotype confers immunological resistance.

The Journal of experimental medicine - 1 Jun 1996

Weisburg J H, Curcio M, Caron P C, Raghu G, Mechetner E B, Roepe P D, Scheinberg D A

Abstract excerpt

Multidrug resistance (MDR), which is due, in part, to the overexpression of P-glycoprotein, confers resistance to a variety of natural product chemotherapeutic agents such as daunorubicin, vincristine, and colchicine. RV+ cells are a P-glycoprotein overexpressing variant of the HL60 myeloid leukemia cell line. In addition to classic MDR, RV+ cells displayed relative resistance to complement-mediated cytotoxicity...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 8676093
DOI: 10.1084/jem.183.6.2699
PMCID: PMC2192622

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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