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Article

MDR1 genotype-related duodenal absorption rate of digoxin in healthy Japanese subjects.

Pharmaceutical research - 1 Apr 2003

Morita Yoshinori, Sakaeda Toshiyuki, Horinouchi Masanori, Nakamura Tsutomu, Kuroda Kohei, Miki Ikuya, Yoshimura Ken, Sakai Toshiyuki, Shirasaka Daisuke, Tamura Takao, Aoyama Nobuo, Kasuga Masato, Okumura Katsuhiko

Abstract excerpt

PURPOSE: Recent clinical studies suggest the importance of the MDR1 genotype at position 3435 (C3435T) in terms of pharmacokinetics, but there is still no consensus in reports on the relationship between the genotype and plasma/serum concentration-time profiles of drugs after conventional oral administration. This study was performed to elucidate the effects of C3435T on the rate of duodenal absorption of digoxin...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 12739761
DOI: 10.1023/a:1023282312757

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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