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Article

MDR1 genotype-related pharmacokinetics: fact or fiction?

Drug metabolism and pharmacokinetics - 1 Dec 2005

Sakaeda Toshiyuki

Abstract excerpt

Multidrug resistant transporter MDR1/P-glycoprotein, the gene product of MDR1, is a glycosylated membrane protein of 170 kDa, belonging to the ATP-binding cassette superfamily of membrane transporters. A number of various types of structurally unrelated drugs are substrates for MDR1, and MDR1 and other transporters are recognized as an important class of proteins for regulating pharmacokinetics. The first...

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Identifiers

PMID: 16415525
DOI: 10.2133/dmpk.20.391

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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