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Article

Meta-analysis of the influence of MDR1 C3435T polymorphism on digoxin pharmacokinetics and MDR1 gene expression.

British journal of clinical pharmacology - 1 Aug 2005

Chowbay Balram, Li Huihua, David Machin, Cheung Yin Bun, Lee Edmund J D

Abstract excerpt

AIMS: Studies revealing conflicting results of the functional significance of MDR1 exon 26 C3435T SNP on the disposition of digoxin in different ethnic groups led us to perform a meta-analysis on published data investigating the influence of C3435T SNP on the pharmacokinetics of digoxin and the expression of MDR1. METHODS: Meta-analysis was performed on data from published studies investigating the influence of...

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Identifiers

PMID: 16042669
DOI: 10.1111/j.1365-2125.2005.02392.x
PMCID: PMC1884933

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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