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Article

MDR1 genotype-related pharmacokinetics and pharmacodynamics.

Biological & pharmaceutical bulletin - 1 Nov 2002

Sakaeda Toshiyuki, Nakamura Tsutomu, Okumura Katsuhiko

Abstract excerpt

The multidrug resistant transporter MDR1/P-glycoprotein, the gene product of MDR1, is a glycosylated membrane protein of 170 kDa, belonging to the ATP-binding cassette superfamily of membrane transporters. MDR1 acts as an energy-dependent efflux pump that exports its substrates out of cells. MDR1...

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Source

Identifiers

PMID: 12419946
DOI: 10.1248/bpb.25.1391

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-12419946-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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