Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Repair system for noncanonical purines in Escherichia coli.

Journal of bacteriology - 1 May 2003

Burgis Nicholas E, Brucker Jason J, Cunningham Richard P

Abstract excerpt

Exposure of Escherichia coli strains deficient in molybdopterin biosynthesis (moa) to the purine base N-6-hydroxylaminopurine (HAP) is mutagenic and toxic. We show that moa mutants exposed to HAP also exhibit elevated mutagenesis, a hyperrecombination phenotype, and increased SOS induction. The E. coli rdgB gene encodes a protein homologous to a deoxyribonucleotide triphosphate pyrophosphatase from Methanococcus...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chromosome Breakage
Share to Coenzymes
Share to Deoxyribonuclease (Pyrimidine Dimer)

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Metalloproteins

Share to Molybdenum Cofactors

Share to Pteridines

Share to Purines

Share to SOS Response, Genetics

Source

Open in PubMed Open full text

Identifiers

PMID: 12730170
DOI: 10.1128/JB.185.10.3101-3110.2003
PMCID: PMC154070

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Repair system for noncanonical purines in Escherichia coli.PMID 12730170Read ↗

Removal of misincorporated ribonucleotides from prokaryotic genomes: an unexpected role for nucleotide excision repair.Semantic proximity Read ↗

RdgB acts to avoid chromosome fragmentation in Escherichia coli.Semantic proximity Read ↗

Hypoxanthine incorporation is nonmutagenic in Escherichia coli.Semantic proximity Read ↗

A multilayered repair system protects the mycobacterial chromosome from endogenous and antibiotic-induced oxidative damage.Semantic proximity Read ↗

Repair of chromosomal abasic sites in vivo involves at least three different repair pathways.Semantic proximity Read ↗

Substrate specificity of RdgB protein, a deoxyribonucleoside triphosphate pyrophosphohydrolase.Semantic proximity Read ↗

Mutagenic cost of ribonucleotides in bacterial DNA.Semantic proximity Read ↗

Polynucleotide phosphorylase is implicated in homologous recombination and DNA repair in Escherichia coli.Semantic proximity Read ↗

Mismatch repair in Gram-positive bacteria.Semantic proximity Read ↗

Abasic sites and strand breaks in DNA cause transcriptional mutagenesis in Escherichia coli.Semantic proximity Read ↗

Homologous recombination prevents methylation-induced toxicity in Escherichia coli.Semantic proximity Read ↗

Roles of Nucleoid-Associated Proteins in Stress-Induced Mutagenic Break Repair in Starving Escherichia coli.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.