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Article

Substrate specificity of RdgB protein, a deoxyribonucleoside triphosphate pyrophosphohydrolase.

The Journal of biological chemistry - 9 Feb 2007

Burgis Nicholas E, Cunningham Richard P

Abstract excerpt

We have previously reported the identification of a DNA repair system in Escherichia coli for the prevention of the stable incorporation of noncanonical purine dNTPs into DNA. We hypothesized that the RdgB protein is active on 2'-deoxy-N-6-hydroxylaminopurine triphosphate (dHAPTP) as well as deoxyinosine triphosphate. Here we show that RdgB protein and RdgB homologs from Saccharomyces cerevisiae, mouse, and human...

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Identifiers

PMID: 17090528
DOI: 10.1074/jbc.M608708200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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