Article
Mismatch repair in Gram-positive bacteria.
Research in microbiology - 1 Jan 2016
Lenhart Justin S, Pillon Monica C, Guarné Alba, Biteen Julie S, Simmons Lyle A
Abstract excerpt
DNA mismatch repair (MMR) is responsible for correcting errors formed during DNA replication. DNA polymerase errors include base mismatches and extra helical nucleotides referred to as insertion and deletion loops. In bacteria, MMR increases the fidelity of the chromosomal DNA replication pathway approximately 100-fold. MMR defects in bacteria reduce replication fidelity and have the potential to affect fitness....
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