Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Polynucleotide phosphorylase is implicated in homologous recombination and DNA repair in Escherichia coli.

BMC microbiology - 4 Apr 2017

Carzaniga Thomas, Sbarufatti Giulia, Briani Federica, Dehò Gianni

Abstract excerpt

BACKGROUND: Polynucleotide phosphorylase (PNPase, encoded by pnp) is generally thought of as an enzyme dedicated to RNA metabolism. The pleiotropic effects of PNPase deficiency is imputed to altered processing and turnover of mRNAs and small RNAs, which in turn leads to aberrant gene expression. However, it has long since been known that this enzyme may also catalyze template-independent polymerization of dNDPs...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bleomycin
Share to DNA, Single-Stranded
Share to Exoribonucleases

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Gene Expression Regulation, Enzymologic

Share to Homologous Recombination

Share to Polyribonucleotide Nucleotidyltransferase

Share to RNA, Bacterial

Share to RNA Stability

Source

Open in PubMed Open full text

Identifiers

PMID: 28376742
DOI: 10.1186/s12866-017-0980-z
PMCID: PMC5379764

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Polynucleotide phosphorylase is implicated in homologous recombination and DNA repair in Escherichia coli.PMID 28376742Read ↗

Polynucleotide phosphorylase protects Escherichia coli against oxidative stress.Semantic proximity Read ↗

Involvement of pnp in survival of UV radiation in Escherichia coli K-12.Semantic proximity Read ↗

Polynucleotide phosphorylase plays an important role in the generation of spontaneous mutations in Escherichia coli.Semantic proximity Read ↗

Bacillus subtilis polynucleotide phosphorylase 3'-to-5' DNase activity is involved in DNA repair.Semantic proximity Read ↗

Genetic analysis of polynucleotide phosphorylase structure and functions.Semantic proximity Read ↗

A novel mutation in the KH domain of polynucleotide phosphorylase affects autoregulation and mRNA decay in Escherichia coli.Semantic proximity Read ↗

A mutation in polynucleotide phosphorylase from Escherichia coli impairing RNA binding and degradosome stability.Semantic proximity Read ↗

Mutational analysis of polynucleotide phosphorylase from Escherichia coli.Semantic proximity Read ↗

Polynucleotide kinase/phosphatase, Pnk1, is involved in base excision repair in Schizosaccharomyces pombe.Semantic proximity Read ↗

Isolation and characterization of a new temperature-sensitive polynucleotide phosphorylase mutation in Escherichia coli K-12.Semantic proximity Read ↗

Repair system for noncanonical purines in Escherichia coli.Semantic proximity Read ↗

Specific binding of 8-oxoguanine-containing RNA to polynucleotide phosphorylase protein.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.