Article
Roles of Nucleoid-Associated Proteins in Stress-Induced Mutagenic Break Repair in Starving Escherichia coli.
Genetics - 1 Dec 2015
Moore Jessica M, Magnan David, Mojica Ana K, Núñez María Angélica Bravo, Bates David, Rosenberg Susan M, Hastings P J
Abstract excerpt
The mutagenicity of DNA double-strand break repair in Escherichia coli is controlled by DNA-damage (SOS) and general (RpoS) stress responses, which let error-prone DNA polymerases participate, potentially accelerating evolution during stress. Either base substitutions and indels or genome rearrangements result. Here we discovered that most small basic proteins that compact the genome, nucleoid-associated proteins...
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