Article
RdgB acts to avoid chromosome fragmentation in Escherichia coli.
Molecular microbiology - 1 Jun 2003
Bradshaw Jill S, Kuzminov Andrei
Abstract excerpt
Bacterial RecA protein is required for repair of two-strand DNA lesions that disable whole chromosomes. recA mutants are viable, suggesting a considerable cellular capacity to avoid these chromosome-disabling lesions. recA-dependent mutants reveal chromosomal lesion avoidance pathways. Here we characterize one such mutant, rdgB/yggV, deficient in a putative inosine/xanthosine triphosphatase, conserved throughout...
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