Article
Hypoxanthine incorporation is nonmutagenic in Escherichia coli.
Journal of bacteriology - 1 Sept 2006
Budke Brian, Kuzminov Andrei
Abstract excerpt
Endonuclease V, encoded by the nfi gene, initiates removal of the base analogs hypoxanthine and xanthine from DNA, acting to prevent mutagenesis from purine base deamination within the DNA. On the other hand, the RdgB nucleotide hydrolase in Escherichia coli is proposed to prevent hypoxanthine an...
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