Article
Sulfotransferase 1A1 (SULT1A1) polymorphism, PAH-DNA adduct levels in breast tissue and breast cancer risk in a case-control study.
Breast cancer research and treatment - 1 Mar 2003
Tang Deliang, Rundle Andrew, Mooney Laverne, Cho Stan, Schnabel Freya, Estabrook Alison, Kelly Amalia, Levine Richard, Hibshoosh Hannina, Perera Frederica
Abstract excerpt
Gene-environment interactions are hypothesized to be major contributors to susceptibility to environmental carcinogens and interindividual variability in cancer risk. We present findings on associations between genetic susceptibility due to inherited polymorphisms of the Phase II detoxification enzyme sulfotransferase 1A1 (SULT1A1), breast cancer risk, and polycyclic aromatic hydrocarbon (PAH)-DNA adducts. A...
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