Article
Interactions between genetic polymorphism of cytochrome P450-1B1, sulfotransferase 1A1, catechol-o-methyltransferase and tobacco exposure in breast cancer risk.
International journal of cancer - 20 Nov 2003
Saintot Monique, Malaveille Christian, Hautefeuille Agnès, Gerber Mariette
Abstract excerpt
Genetic polymorphisms of enzymes involved in the metabolism of xenobiotics and estrogens might play a role in breast carcinogenesis related to environmental exposures. In a case-only study on 282 women with breast cancer, we studied the interaction effects (ORi) between smoking habits and the gen...
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