Article
The association between glutathione S-transferase M1 genotype and polycyclic aromatic hydrocarbon-DNA adducts in breast tissue.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Oct 2000
Rundle A, Tang D, Zhou J, Cho S, Perera F
Abstract excerpt
A major goal in molecular epidemiology is to identify preventable environmental risk factors and susceptible subpopulations. In a hospital-based molecular epidemiological case-control study of breast cancer, we investigated the relationship between DNA damage from exposure to polycyclic aromatic hydrocarbons (PAHs) and susceptibility attributable to inherited deletion of the xenobiotic detoxifying gene,...
Topics
- Adult
- Aged
- Breast
- Breast Neoplasms
- Case-Control Studies
- DNA Adducts
- DNA Damage
- Female
- Genetic Predisposition to Disease
- Genotype