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Article

Interactions between exposure to polycyclic aromatic hydrocarbons and xenobiotic metabolism genes, and risk of breast cancer.

Breast cancer (Tokyo, Japan) - 1 Jan 2022

Lee Derrick G, Schuetz Johanna M, Lai Agnes S, Burstyn Igor, Brooks-Wilson Angela, Aronson Kristan J, Spinelli John J

Abstract excerpt

PURPOSE: Polycyclic aromatic hydrocarbons (PAHs) are a group of environmental pollutants associated with multiple cancers, including female breast cancer. Several xenobiotic metabolism genes (XMGs), including the CYP450 family, play an important role in activating and detoxifying PAHs, and variations in the activity of the enzymes they encode can impact this process. This study aims to examine the association...

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PMID: 34351578
DOI: 10.1007/s12282-021-01279-0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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