Article
Do single nucleotide polymorphisms in xenobiotic metabolizing genes determine breast cancer susceptibility and treatment outcomes?
Cancer investigation - 1 Oct 2008
Singh Virendra, Parmar Devendra, Singh Mahendra Pratap
Abstract excerpt
SNPs in CYP1A1, CYP2A1, CYP2B6, CYP2C, CYP2D6, CYP3A, GSTM1, GSTT1, GSTP1, SULT1A1, SULT1A2, UGT, and MTHFR are associated with breast cancer susceptibility; however, lack of such associations are also reported in some populations. The contradictory findings are explained on the basis of ethnic variation among populations and due to lack of proper sample size, detailed genotype-phenotype combinations and...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
