Article
Promoter (4G/5G) plasminogen activator inhibitor-1 genotype and plasminogen activator inhibitor-1 levels in blacks, Hispanics, and non-Hispanic whites: the Insulin Resistance Atherosclerosis Study.
Circulation - 20 May 2003
Festa Andreas, D'Agostino Ralph, Rich Steven S, Jenny Nancy S, Tracy Russell P, Haffner Steven M
Abstract excerpt
BACKGROUND: The 4G/5G polymorphism of the plasminogen activator inhibitor-1 (PAI-1) gene has been related to cardiovascular disease. METHODS AND RESULTS: Insulin resistance was measured with a frequently sampled intravenous glucose tolerance test in the Insulin Resistance Atherosclerosis Study (IRAS), and PAI-1 4G/5G promoter genotype was established by allele-specific polymerase chain reaction amplification of...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.