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Article

Determinants of plasminogen activator inhibitor 1 activity in treated NIDDM and its relation to a polymorphism in the plasminogen activator inhibitor 1 gene.

Diabetes - 1 Jan 1995

Panahloo A, Mohamed-Ali V, Lane A, Green F, Humphries S E, Yudkin J S

Abstract excerpt

Plasminogen activator inhibitor 1 (PAI-1) activity is increased in patients with non-insulin-dependent diabetes mellitus (NIDDM) and may contribute to their excess risk of cardiovascular disease. We examined the determinants of PAI-1 activity in 146 NIDDM subjects by using specific assays of insulin and intact and des-31,32-proinsulin and measures of insulin resistance, relating these measurements to serum...

Topics

Adult
Aged
Base Sequence
Diabetes Mellitus, Type 2
Female
Genotype
Humans
Insulin
Male
Middle Aged
Molecular Sequence Data
Plasminogen Activator Inhibitor 1

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Polymorphism, Genetic

Promoter Regions, Genetic

Regression Analysis

Triglycerides

Source

Identifiers

PMID: 7813812
DOI: 10.2337/diab.44.1.37

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7813812-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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Determinants of plasminogen activator inhibitor 1 activity in treated NIDDM and its relation to a polymorphism in the plasminogen activator inhibitor 1 gene.PMID 7813812Read ↗

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