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Article

Association analysis of the plasminogen activator inhibitor-1 4G/5G polymorphism in Hispanics and African Americans: the IRAS family study.

Human heredity - 1 Jan 2004

Bensen Jeannette T, Hsu Fang-Chi, Brown W Mark, Sutton Beth S, Norris Jill M, Tracy Russell P, Jenny Nancy S, Saad Mohammed F, Haffner Steven, Bowden Donald W, Langefeld Carl D

Abstract excerpt

OBJECTIVE: Plasminogen activator inhibitor type-1 (PAI-1) plays a central role in fibrolysis and has recently been hypothesized to influence components of the insulin resistance syndrome. We consider whether the 4G/5G polymorphism influences components of insulin resistance and obesity solely through PAI-1 protein levels or also though a secondary pathway. In addition, we explore whether transforming growth...

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Identifiers

PMID: 15297806
DOI: 10.1159/000079243

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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