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Article

Allelic frequency of the PAI-1 4G/5G promoter polymorphism in patients with type 2 diabetes mellitus and lack of association with PAI-1 plasma levels.

Endocrine research - 1 Aug 2004

Zietz B, Buechler C, Drobnik W, Herfarth H, Schölmerich J, Schäffler A

Abstract excerpt

Plasminogen activator inhibitor-1 (PAI-1) levels were found to be associated with obesity, indicating that adipocytes might influence PAI-1 plasma levels. In addition, the 4G/5G promoter polymorphism of the PAI-1 gene possibly modulates PAI-1 gene transcription and, as a consequence, PAI-1 plasma levels. Metabolic parameters, diabetes complications, PAI-1 plasma levels, and PAI-1 promoter genotypes were...

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Share to Coronary Disease
Share to Diabetes Mellitus, Type 2

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Diabetic Retinopathy

Share to Gene Frequency

Share to Plasminogen Activator Inhibitor 1

Share to Polymorphism, Genetic

Share to Promoter Regions, Genetic

Share to Statistics, Nonparametric

Source

Identifiers

PMID: 15554360
DOI: 10.1081/erc-200035728

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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