Article
Promoter (4G/5G) plasminogen activator inhibitor-1 genotype in Pima Indians: relationship to plasminogen activator inhibitor-1 levels and features of the insulin resistance syndrome.
Diabetologia - 1 Dec 1996
McCormack L J, Nagi D K, Stickland M H, Mansfield M W, Mohamed-Ali V, Yudkin J S, Knowler W C, Grant P J
Abstract excerpt
Elevated plasminogen activator inhibitor-1 may contribute to vascular disease in diabetes mellitus. Pima Indians have a low incidence of cardiovascular disease despite having a high prevalence of non-insulin-dependent diabetes mellitus (NIDDM) which in this population is not associated with eleva...
Topics
- Adult
- Aged
- Arizona
- Base Sequence
- Cohort Studies
- DNA Primers
- Diabetes Mellitus, Type 2
- Female
- Genotype
- Humans
- Indians, North American
- Insulin Resistance
- Male
- Middle Aged
- Plasminogen Activator Inhibitor 1