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Article

Alterations of arterial physiology in osteopontin-null mice.

Arteriosclerosis, thrombosis, and vascular biology - 1 Jun 2003

Myers Daniel L, Harmon Kelley J, Lindner Volkhard, Liaw Lucy

Abstract excerpt

OBJECTIVE: In this study, we characterized the effects of an osteopontin (OPN)-null mutation in normal arterial function and remodeling in a murine model. METHODS AND RESULTS: OPN-null mutant mice were compared with wild-type mice before and after carotid artery ligation. Before ligation, OPN-null mice had increased heart rate, lower blood pressure, and increased circulating lymphocytes compared with wild-type...

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Source

Identifiers

PMID: 12714436
DOI: 10.1161/01.ATV.0000073312.34450.16

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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