Article
Characterization of the mouse analogues of CD59 using novel monoclonal antibodies: tissue distribution and functional comparison
23 Apr 2003
Abstract excerpt
CD59, the sole membrane regulator of the membrane attack complex of complement, is broadly and abundantly expressed in man and other mammals. In mouse, CD59 is encoded by two homologous genes. The expression patterns and functional roles of the proteins encoded by these genes, mCD59a and mCD59b, have not been well characterized. Here we describe the generation of monoclonal and polyclonal antibodies detecting...
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