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Article

Deletion of the gene encoding CD59a in mice increases disease severity in a murine model of rheumatoid arthritis.

Arthritis and rheumatism - 1 Sept 2004

Williams A S, Mizuno M, Richards P J, Holt D S, Morgan B P

Abstract excerpt

OBJECTIVE: To investigate the roles of CD59a in the protection of joint tissue in the context of murine antigen-induced arthritis (AIA). METHODS: AIA was triggered in CD59a-deficient (CD59a(-/-)) mice and in CD59a-sufficient (CD59a(+/+)) controls; the course and severity of disease were compared between groups. The effects on arthritis of restoring CD59 to the joint in CD59a(-/-) mice by use of a...

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Share to CD59 Antigens
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 15457473
DOI: 10.1002/art.20478

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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