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Article

Congenital CD59 Deficiency.

Hematology/oncology clinics of North America - 1 Jun 2015

Höchsmann Britta, Schrezenmeier Hubert

Abstract excerpt

The severe clinical symptoms of inherited CD59 deficiency confirm the importance of CD59 as essential complement regulatory protein for protection of cells against complement attack, in particular protection of hematopoietic cells and human neuronal tissue. Targeted complement inhibition might become a treatment option as suggested by a case report. The easy diagnostic approach by flow cytometry and the advent of...

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Topics

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Share to Anemia, Hemolytic
Share to Antibodies, Monoclonal, Humanized
Share to CD59 Antigens

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Complement System Proteins

Share to Flow Cytometry

Share to Models, Immunological

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Source

Identifiers

PMID: 26043388
DOI: 10.1016/j.hoc.2015.01.006

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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