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Article

Deficiencies in the CD19 complex.

Clinical immunology (Orlando, Fla.) - 1 Oct 2018

Wentink Marjolein W J, van Zelm Menno C, van Dongen Jacques J M, Warnatz Klaus, van der Burg Mirjam

Abstract excerpt

Signaling via the CD19-complex, consisting of CD19, CD81, CD21 and CD225, is critically important for B-cell development, differentiation and maturation. In this complex, each protein has its own distinct function. Over the past decade, 15 patients with antibody deficiency due to deficiencies in the CD19-complex have been described. These patients have deficiencies in different complex-members, all caused by...

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Share to Antibodies
Share to Antigens, CD19
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Immunity, Humoral

Share to Immunologic Deficiency Syndromes

Share to Lymphocyte Activation

Share to Multiprotein Complexes

Share to Receptors, Antigen, B-Cell

Source

Identifiers

PMID: 30075290
DOI: 10.1016/j.clim.2018.07.017

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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