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Article

Haplotypic analysis of the TNF locus by association efficiency and entropy.

Genome biology - 1 Jan 2003

Ackerman Hans, Usen Stanley, Mott Richard, Richardson Anna, Sisay-Joof Fatoumatta, Katundu Pauline, Taylor Terrie, Ward Ryk, Molyneux Malcolm, Pinder Margaret, Kwiatkowski Dominic P

Abstract excerpt

BACKGROUND: To understand the causal basis of TNF associations with disease, it is necessary to understand the haplotypic structure of this locus. We genotyped 12 single-nucleotide polymorphisms (SNPs) distributed over 4.3 kilobases in 296 healthy, unrelated Gambian and Malawian adults. We generated 592 high-quality haplotypes by integrating family- and population-based reconstruction methods. RESULTS: We found...

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Identifiers

PMID: 12702205
DOI: 10.1186/gb-2003-4-4-r24
PMCID: PMC154575

Genes

TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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