Article
A genotype-based approach to assessing the association between single nucleotide polymorphisms.
Human heredity - 1 Jan 2009
Wellek Stefan, Ziegler Andreas
Abstract excerpt
Measuring the extent of linkage disequilibrium (LD) between single nucleotide polymorphisms (SNPs) is of considerable importance, and many different between SNP association measures including Lewontin's D' and Pearson's correlation coefficient rho have been proposed. The vast majority of these association measures are based on haplotypes instead of genotypes. If no family data are available, the required...
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