Article
The effect of haplotype-block definitions on inference of haplotype-block structure and htSNPs selection.
Molecular biology and evolution - 1 Jan 2005
Ding Keyue, Zhou Kaixin, Zhang Jing, Knight Joanne, Zhang Xuegong, Shen Yan
Abstract excerpt
It has been recently suggested that the human genome is organized as a series of haplotype blocks, and efforts to create a genome-wide haplotype map are already underway. Several computational algorithms have been proposed to partition the genome. However, little is known about their behaviors in relation to the haplotype-block partitioning and haplotype-tagging SNPs selection. Here, we present a systematic...
Topics
- Algorithms
- Chromosome Mapping
- Computational Biology
- Computer Simulation
- Genetic Markers
- Genetic Variation
- Genetics, Population
- Genome, Human
- Humans
- Models, Genetic
- Polymorphism, Single Nucleotide