Article
A sparse marker extension tree algorithm for selecting the best set of haplotype tagging single nucleotide polymorphisms.
Genetic epidemiology - 1 Dec 2005
Hao Ke, Liu Simin, Niu Tianhua
Abstract excerpt
Single nucleotide polymorphisms (SNPs) play a central role in the identification of susceptibility genes for common diseases. Recent empirical studies on human genome have revealed block-like structures, and each block contains a set of haplotype tagging SNPs (htSNPs) that capture a large fraction of the haplotype diversity. Herein, we present an innovative sparse marker extension tree (SMET) algorithm to select...
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