Article
A sparse marker extension tree algorithm for selecting the best set of haplotype tagging single nucleotide polymorphisms.
Genetic epidemiology - 1 Dec 2005
Hao Ke, Liu Simin, Niu Tianhua
Abstract excerpt
Single nucleotide polymorphisms (SNPs) play a central role in the identification of susceptibility genes for common diseases. Recent empirical studies on human genome have revealed block-like structures, and each block contains a set of haplotype tagging SNPs (htSNPs) that capture a large fractio...
Topics
- Algorithms
- Empirical Research
- Haplotypes
- Humans
- Polymorphism, Single Nucleotide
