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Article

The Wlds mutation delays robust loss of motor and sensory axons in a genetic model for myelin-related axonopathy.

The Journal of neuroscience : the official journal of the Society for Neuroscience - 1 Apr 2003

Samsam Mohtashem, Mi Weiqian, Wessig Carsten, Zielasek Jürgen, Toyka Klaus V, Coleman Michael P, Martini Rudolf

Abstract excerpt

Mice deficient in the peripheral myelin component P0 mimic severe forms of inherited peripheral neuropathies in humans, with defective myelin formation and consequent axonal loss. We cross-bred these mice with the spontaneous mutant C57BL/Wld(s) typically showing protection from Wallerian degeneration because of fusion of the ubiquitination factor E4B (Ube4b) and nicotinamide mononucleotide adenylyltransferase...

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Identifiers

PMID: 12684470
PMCID: PMC6742108

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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The Wlds mutation delays robust loss of motor and sensory axons in a genetic model for myelin-related axonopathy.PMID 12684470Read ↗

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