Article
Human homologue of a gene mutated in the slow Wallerian degeneration (C57BL/Wld(s)) mouse.
Gene - 6 Feb 2002
Fernando F Shama, Conforti Laura, Tosi Sabrina, Smith A David, Coleman Michael P
Abstract excerpt
The slow Wallerian degeneration mouse (C57BL/Wld(s)) is a mutant strain of mouse, with the unique phenotype of prolonged survival of the distal axon following axotomy. The causative mutation is an 85 kb tandem triplication on distal mouse chromosome 4. The dominant slow Wallerian degeneration phenotype is conferred by a hybrid gene within the triplication, comprising a gene of previously unknown function,...
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